Instrumentation

	We have access to a PIONEER continuous flow Peptide Synthesis System instrument (departmental equipment).  Here we synthesize isotopically labeled fragments of the β2 microglobulin protein.
The BioCAD Sprint HPLC (departmental equipment) is used to purify our synthetic peptides.
	This HP 8452A UV/Vis is used to confirm fibril formation in solution via observation of a red-shift of the congo red spectrum upon binding to amyloid fibrils.
Here is our 359.5 MHz widebore NMR magnet (8.44 T) with a 3 channel Tecmag Apollo console.  It does not have a lock channel, so it is primarily suitable only for solid-state NMR experiments.
	Our homebuilt two channel (HX) Magic Angle Spinning probe for the 360 MHz widebore magnet.  It has a 3.2mm stator which will spin the sample at speeds of up to 24 kHz.  The probe is removed from the magnet for a sample change and is then returned into the magnet from below.
Filters, duplexer (passive switch), directional couplers and signal pre-amplifier for each NMR frequency.
	The HP8712ET spectrum analyzer is used for testing during the manufacture of probes and other homebuilt RF devices.  It can also be used for tuning the probe.